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05 May 2008, 06:52
Anti-fibrotic Mechanism Of A Chinese Medicinal Herb May Inspire Drug Development
Hepatic fibrosis, which can lead to portal hypertension or cirrhosis, is a wound-healing response to continuing liver wound due to a diversification of insults. The altered balance between the synthesis and degeneracy of matrix proteins (mainly collagens) is the major pathogenic feature in the hepatic fibrosis process.
Although exceptional progress has been made recently in understanding the mechanisms of hepatic fibrosis and while numerous agents annex been studied, very few effective antifibrogenic drugs have been approved for use in humans. Previous research has showed that Cpd 861, which was formulated beside one the authors (Dr.
Bao-En Wang) in accordance with traditional Chinese medical theory, can significantly improve the clinical manifestations and biochemical parameters of patients with hepatic fibrosis.
Their virgin drudgery found that the antifibrotic function of Cpd 861 is mediated not only by inhibiting collagen synthesis (by downregulating collagen type III gene expression) however also alongside enhancing the degradation of collagens (by increasing the term of matrix metalloproteinase-1, which is an enzyme that degrades collagens).
These result are at variance from those of Western antifibrogenic drugs (such as interferon- gamma).
The inventor explain that the herbs used to prepare Cpd 861 acquire been worn for thousands of senility in Habitual Chinese Medicine, and the results of this research could allow for the development of emphatic antifibrogenic drugs from Chinese sanative herbs.
Using human hepatic stellate chamber and a real-time quantitative PCR method, this check was performed by physicians from the Beijing Genomics Institute, the Liver Research Center of the Beijing Congeniality Hospital, and the Institute of Medicinal Plant Development of the Chinese Academy of Medical Sciences, China.
Further research should be done to explain the machine for Cpd 861's regulation of collagen-related gene expression and to identify the vigorous antifibrotic ingredient in Cpd 861. Reference: Wang L, Wang BE, Wang J, Xiao PG, Tan XH.
Herbal make up 861 regulates the mRNA expression of collagen synthesis and degradation linked genes in anthropoid hepatic stellate cells. Macrocosm J Gastroenterol 2008; 14(10): 1790-1794 http:
1007-9327 14 1790.asp Adapted from matter provided by Sphere Journal of Gastroenterology, via EurekAlert!, AAAS.
18, 2007) - Using Chinese herbs either alone or in conjunction with chemotherapy may lift guard a bosom cancer patient's bone marrow and immune system, as blooming as improving the woman's overall merit of.
Chinese Medicine Compound Has Satisfactory Anti-cancer Effects On Hepatocellular Carcinoma (Oct. 16, 2007) - Traditional Chinese medicine is world renowned. It has aftermath on some diseases, but some of the reasons are much unknown. Human hepatocellular carcinoma is a challenging disease worldwide and.
A Rosetta Stone For Routine Chinese Medicine (Oct.
30, 2007) - Scientists have "decoded" the inscrutable speaking of usual Chinese medicine, revealing its strong chemical bottom in a way that may help scientists excavation age-old Chinese medicines to. New Drugs Awaiting Discovery In Chinese Herbs?
Jan. 23, 2007) - The elementary large-scale machine screenings of Chinese herbs -- commonly euphemistic pre-owned in traditional Chinese medicine -- has revealed a broad divergency of compounds with potential for use in treating HIV AIDS,.
From http://sciencedaily.com/releases/2008/04/080430094820.htm
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30 April 2008, 15:51
Chinese medicine: The private to wonderful skin? - GreenDAY - MSNBC.com
Held in a easy one-ounce push container emblazoned with a tiny Chinese character, it dominates my bathroom cabinet with its moisturizing skilfulness and transmute my dehydrated postnatal skin into a configuration of supple exquisiteness with a few powerful drops.
And just as a novel has to be unusually spectacular to hold my attention these days, my number-one moisturizer obligated to surprize and joy me while containing nothing but the finest of organic ingredients.
Created by Beth Hooper and Laura Kauffmann â " acupuncturists and Chinese herbalists â " She Capital Beautyâ s facial serum is the next generation of skin care.
The women behind She (pronounced â shayâ ) corner created a line of moisturizing and cleansing products that are based on the philosophy of Traditional Chinese Medicine (TCM), which means that my prized facial serum is not peerless made from the best organic and all-natural ingredients, but also embrace mother-of-pearl, which the Chinese accept euphemistic pre-owned championing centuries to enhance the skinâ s beauty.
Since 2006, Hooper and Kauffmann include been lovingly handcrafting their TCM-influenced class of products, including sugar scrubs, washing grains, bath salts, lip balm and the delectable facial serum (not a lotion, not an oil, but an immensely effective moisturizer for face, throat, still under eyes).
Their products use Chinese herbs like the bo he found in the Lemongrass-Mint Sugar Scrub, and dang gui, which is tucked into the herbal lip balm. The former herb helps to reduce inflammation and alleviate pain, while the modern assist in regenerating new derma cells.)
For the uninitiated, Hooper and Kauffmann have distilled TCM into a palatable definition: The fresh practice of ancient curative techniques from China, whose tradition began on top of 3,000 years ago, TCM owes its foundation to four modalities which comprise a holistic medical system:
Chinese herbal medicine.â In developing their line of expensive skin affliction products the ladies turned to â Mei Rong,â the cosmetology section of TCM dedicated to maintaining the skinâ s juvenescence and well-being.
Hooper recently took some time to communicate me all about it. W hat inspired you to start a fleece care wrinkle based on TCM? Both my partner and I are Chinese medicine practitioners (certified herbalists and licensed acupuncturists).
Our skin was changing as we got older, and when we looked at our options for skin burden there were not enough organic alternatives. We were looking for products that contained no parabens or synthetics. It then occurred to us that we could do so much whether we used Chinese herbs in products.
At times a company would launch ginger in something, but no sole was using Chinese herbs in a broad scale in skin anguish products. At anterior we wanted our output representing ourselves, and then we wanted to share them with others.
Most Chinese herbs are used for dermatological emanation â " they are medicinally focused â " but we knew that wouldnâ t have an ask for the public.
We wanted to effect something that wasnâ t just functional but further very luxurious for people to use. Sheâ in Chinese have in mind luxury. How do you follow the philosophy of Chinese medicine in your products?
As we age we lose our yin (the dampish substance, also confessed as the female part of our body) and our skin starts to dry out.
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25 April 2008, 04:14
Natural Newswire: Herb Pharm Launches Two New Alcohol-Free Herbal Glycerite Extracts
April 24, 2008 Natural Newswire - Herb Pharm, producer of America's number one selling trade-mark of liquid herbal extracts, today announced the introduction of two latest alcohol-free herbal glycerite extracts -- Green Tea and Rhodiola root.
For consumers who prefer liquid herbal extracts, they testament now have broad access to alcohol-free liquid extracts of these two very usual herbs. Both products began shipping to natural result retailers in early April, and are also available online at www.herb-pharm.com. Green Tea is a flush source of free-radical scavenging antioxidants.
Herb Pharm's alcohol-free Green Tea glycerite is made from the young leaves of the Camellia sinensis plant, which are certified organically grown at Ambootia Tea Plantation in Darjeeling, India.
To assure optimal quality, the leaves are hand-harvested at their peak of power and then promptly heat-dried to stabilize and safeguard their antioxidant catechins and flavonoids.
Rhodiola root has a long history of use in enhancing intellectual and physical energy and stamina.
Herb Pharm's alcohol-free Rhodiola glycerite is prepared from the dried apricot roots of Rhodiola rosea plants, which are harvested in their luxuriant inherent habitat in the Russian Arctic Circle.
To assure optimal eradication of Rhodiola's antioxidant flavonoids and delicate rose flavor, the roots are hand-harvested at their peak of potency, are carefully shade-dried, and are then shipped directly to our facility for prompt extraction. Our alcohol-free herbal glycerites are further similar to our liquid herbal extracts and they can be used in the same way," says medical herbalist, Ed Smith, founder and co-owner of Herb Pharm.
The difference is a slightly adjusted extraction formation which enables us to extract the herbs with natural, GMO-free coconut-derived glycerine instead of alcohol."
About Herb Pharm Located in rural southern Oregon, Herb Pharm is a certified organic grower of medicinal herbs, and produces a line of herbal extracts and herbal healthcare products which are distributed beneath the Herb Pharm brand.
We grow most of our herbs on our 85-acre Oregon Tilth certified biological farm and also do practical research on the propagation and cultivation of endangered dense therapeutic plants.
Expanded clue is available at www.herb-pharm.com. MEDIA CONTACT: 179, mgillette herb-pharm.com April 24, 2008 Permalink TrackBack TrackBack URL for this entry: 17553 28470124 Listed below are links to weblogs that reference Herb Pharm Launches Two New Alcohol-Free Herbal Glycerite Extracts :
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From http://naturalnewswire.com/2008/04/herb-pharm-laun.html